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Glycation and Diabetes: A Vicious Cycle In this episode of The College of Glycation, Dr. Paul Reynolds turns the spotlight on the destructive interplay between glycation and diabetes, revealing how advanced glycation end products (AGEs) accelerate complications like neuropathy, retinopathy, a
Time: 25:58
In this episode of The College of Glycation, Dr. Paul Reynolds turns the spotlight on the destructive interplay between glycation and diabetes, revealing how advanced glycation end products (AGEs) accelerate complications like neuropathy, retinopathy, and nephropathy. He explains how elevated blood sugar levels fuel AGE formation, setting off a chain reaction of tissue damage, inflammation, and oxidative stress—especially when insulin resistance is already in play. Backed by clinical studies and decades of metabolic research, Dr. Reynolds unpacks the biochemical feedback loop that makes glycation both a cause and consequence of worsening diabetes.
Listeners will come away with a powerful understanding of why glycation is more than a side effect—it's a core driver of diabetic complications. From the AGE-RAGE signaling pathway to tools like skin autofluorescence and strategies to lower dietary AGE intake, this episode equips you with practical science to fight back. Whether you're navigating type 1 or type 2 diabetes, or seeking to prevent long-term damage, Dr. Reynolds delivers compelling, evidence-based insights to help break the cycle of sugar-driven disease.
GUID: a7927f1a-1057-49d5-9d86-28cd1e9c6ead
Release Date: 11/06/2025, 19:30:00
